ABSTRACT
[Objective] To evaluate the range of vaccination age for hand-foot and mouth disease ( HFMD) . [ Methods] HFMD data in 2010-2012 were obtained from Yinzhou District as the model for analysis of HFMD's age distribution characteristics , especially of severe and death cases .Logistic regres-sion method was used to calculate the relative risk values of age groups from 0 to 11 months of age . [ Re-sults] In our investigation , 95.66%of cases were distributed between 0-5 years.Average incidence of HFMD for different age groups, 0 -4 years old was 44.57/1000, 5 years old 9.79/1000, 6 years old 6 .84/1000 , and average incidence no more than 3/1000 after 7 years of age .Average incidence for death and severe cases was 22 months of age .The risk of HEMD started to greatly increase with age from 0 to 11 months old, and became much more dangerous after 10 months of age. [Conclusion] The initial vacci-nation age for HEMD should be between 6 to 10 months of age , the appropriate crowd for HFMD vaccination between 6 to 71 months of age, and vaccination is not of much significance for children after 71 months (6 years) of age.